"Efecto de la suplementaciòn con harina de càscara de mango(mangifera indica L)sobre la funciòn y estructura renal de pollos de engorde".

Abstract

The effect of supplementation with mango peel meal (MCH) on renal function was evaluated in 168 broilers raised in tropical conditions, through relative kidney weight, serum concentration of electrolytes (sodium, potassium, chloride and calcium), urea, uric acid, creatinine, creatine kinase (CK) and renal structure, by histopathological analysis of glomeruli, interstitium and renal tubules. At 28 days of age, they were randomly distributed into six treatments with 4 replicates: T1 male HCM 0%, T2 male HCM 1%, T3 male HCM 2%, T4 female HCM 0%, T5 female HCM 1% and T6 HCM 2%, generated by combining the factors: sex (S) and HCM dose (0%, 1% and 2%). At 56 days of age, and after a 10-hour fast, 2 animals per replicate were sacrificed. The results were analyzed by analysis of variance (ANOVA), using a completely randomized design with a 2x3 factorial arrangement, except for serum uric acid concentration, creatine kinase (CK) and relative kidney weight, which were evaluated by the Kruskal-Wallis nonparametric test and Fisher's exact test for the comparison of histopathological lesions between unsupplemented and HCM-supplemented chickens. It was observed that the serum concentration of potassium (K) was higher in females and birds supplemented with 2% HCM (p<0.05), while chlorine (Cl) was higher in males (p<0.05) and the interaction of S x HCM (p= 0.067), evidenced the higher concentration of Cl in supplemented males, on the contrary, in supplemented females the lower concentration. Regarding serum urea levels, it was higher in females (p<0.05) and in non-supplemented birds (p<0.1). The interaction of S x HCM, in urea (p<0.05) and uric acid (p<0.1), pointed to the non-supplemented females with the highest mean. No differences were observed in creatinine, creatine kinase (CK), relative kidney weight and glomeruli diameter. Among the lesions evaluated at the renal level, a higher incidence of interstitial nephritis was found in supplemented animals compared to non-supplemented animals (p<0.05). It is concluded that the supplementation with HCM at 1 and 2%, improves the renal profile in females, without modifying the PR of the kidney; the addition of HCM at 2% decreased the glomerular diameter, without attenuating the manifestation of histopathological lesions, except tubular nephritis, in which its frequency increased.