Laboratorio Clinico

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Browsing Laboratorio Clinico by Author "ÁLAVA PINCAY, MARÍA JOSÉ"
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    KLEBSIELLA PNEUMONIAE EN PACIENTES DE CUIDADOS INTENSIVOS, HOSPITAL GENERAL DE PORTOVIEJO
    (Universidad Técnica de Manabí, 2020) ÁLAVA PINCAY, MARÍA JOSÉ ; LÓPEZ SORNOZA, MELISSA NICOLE ; PACHAY SOLÓRZANO, JORGE
    K. pneumoniae is a gram negative bacterium that belongs to the group of Enterobacteriaceae, and is one of the main nosocomial pathogens that cause serious infections in intensive care units (ICU). Target site for colonization and appearance of epidemic outbreaks because it is a critical care unit and because of the multiple procedures carried out that can establish entry doors for colonization by this microorganism. The main objective of this research work is to determine the frequency of K. pneumoniae in intensive care patients, General Hospital of Portoviejo during the period January 2018 - January 2019, through a field, observational, descriptive, retrospective study with the purpose of Obtain pertinent information regarding the isolation of this bacterial genus. The study was carried out in a total of 266 patients, of which 25 positive cases of K. pneumoniae were detected. The results obtained showed that there is no statistically significant difference in relation to sex, being the male the one that prevailed with 52%, while the female sex in 48%. The age range where the highest incidence of infection occurred was greater than 60 years. The most common type of biological sample where isolation of this microorganism was obtained was tracheal aspirate. Among the most frequent comorbidities prior to taking the sample for culture were arterial hypertension and diabetes mellitus. The highest resistance observed in the 25 strains corresponds to the group of beta-lactam antibiotics and beta-lactamase inhibitors such as: Amoxicillin + Clavulanic acid: (84%) and third generation Cephalosporins (72%). The drug that showed the highest sensitivity was Colistin and Tigecycline (100%). Concluding that the frequency of this bacterium in this health institution was 9%; Therefore, control measures must continue to be implemented to eradicate resistance mechanisms, such as the application of primary containment measures, as well as the rational use of antibiotics