DETERMINACIÓN DE NT-PROBNP EN ADULTOS MAYORES DEL CENTRO GERONTOLÓGICO GUILLERMINA LOOR DE MORENO DE PORTOVIEJO

Abstract

Heart failure (HF) is a chronic condition that is characterized because the heart does not pump blood with the necessary efficiency, is one of the most disabling, costly, frequent and lethal diseases facing the health team, the IC it is a progressive and lethal disorder, even with adequate treatment. It is the first cause of hospital admission in people over 65 years of age and represents just over 2% of national health expenditure. The utility of the N-terminal prohormone of brain natriuretic peptide (NT-proBNP) for the diagnosis of heart failure has been demonstrated. However, the values of these markers differ according to the characteristics of the patients and the severity of the disease. The objective of this study is to determine the utility of the blood measurement of NT-proBNP to diagnose heart failure in elderly patients of the gerontological center Guillermina Loor de Moreno. To carry out this study, analyzes of NT-proBNP, creatinine, urea, hemoglobin, glucose and sodium were performed in 47 blood samples of patients from the gerontological center in the period October to December 2017. The values and the possible association with other diseases. The values of demographic, analytical and clinical variables were compared. The clinical manifestations and personal pathological background associated to the suffering of heart failure were analyzed. The NT-proBNP value was associated with the presence of anemia, creatinine greater than 2 mg / dL and hyponatremia. The average age of the patients was 79 years, predominantly male, with associated comorbidity and a certain degree of dependence, although age was not a factor that influenced the probability of having an increase in the plasma NT-proBNP value and therefore both of the latent risk of suffering or not heart failure. In the obtained results it was possible to demonstrate that the value of NT-proBNP showed to be a complementary analyte of great clinical importance for the evaluation and the integral health care of the elderly