FENOTIPOS SANGUÍNEOS DEL SISTEMA RH EN LA POBLACIÓN MANABITA, EN EL HOSPITAL ONCOLÓGICO DE SOLCA-PORTOVIEJO EN EL PERIODO JUNIO 2017-JUNIO 2018

Abstract

The present investigation revealed the importance in the determination of the most common blood phenotypes in the Manabi population and to avoid post-transfusion hemolytic reactions, hemolytic anemia of the newborn and subsequent sensitization of poly transfused patients. The objective of the present study was to identify the blood phenotypes of the Rh system (CcEe) most common in the Manabi population, obtained at the Oncology Hospital of SOLCA Portoviejo during the period June 2017 to June 2018. In the same way, the frequency of the phenotypes was determined according to the Rh and ABO system of blood unit receptors, as well as the classification according to gender and demographic characteristics of each patient. The existence of blood compatibility of the Rh system phenotypes between donors and recipients of both positive and negative blood units was demonstrated using the ambipective method. A total of 1554 patients who received blood units were analyzed in the Oncology Hospital of SOLCA. Of these, 1367 belong to the Manabi population. The blood phenotypes of the Rh system were determined by tube hemagglutination. The data collected were and processed statistically in Excel 2013 and digitized in Word 2013. It was found in the total samples analyzed that the most common blood phenotype in the Manabi population was "CcEe", followed by "Ce" with 34% and 26% respectively. From the same shape according to the Rh negative system, the most common was "ce" with 84%, and in Rh positive patients it was "CcEe". It was also possible to determine that in the Manabi population in the classification corresponding to the ABO system as well as by sex, the blood phenotype of the most common Rh system does not show variation in relation to the Rh positive and negative units. The result that had the greatest impact in the research refers to the existence of blood compatibility of the Rh system phenotypes in 85% of the sample, demonstrating that if phenotyping is performed in all transfusion medicine services we will reduce the percentage of blood transfusions not phenotypically compatible. The remaining 15% is equivalent to phenotypically incompatible units, and the most common Rh system antigens that were transfused are "C" and "E", of which the latter has greater immunogenic power after antigen D and "c"